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Fetuin A Recombinant Protein

Product Specifications

Background

Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.

NCBI Gene ID

11625

Swiss Prot

P29699

Accession Number

P29699

Tag

C-10 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-714

Calculated Molecular Weight

36.7 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Alpha-2-HS-glycoprotein

NCBI Organism

Mus musculus

Other Product Names

Alpha-2-HS-glycoprotein, Ahsg, Countertrypin, Fetuin-A, Fetua

Species

Mouse

Physical Properties

Lyophilized

CAS Number

9000-83-3

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