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NaPi2b-IN-2

Product Specifications

UNSPSC Description

NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/napi2b-in-2.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=C(C2=C(S1)CC(C)(CC2)C)C(C3=CN(C4=CC(C(F)(F)F)=C(Cl)C=C4)N=C3)=O)C5=CC(CN(C(CC)CC)CCN(C)C(CCC(O)=O)=O)=CC=C5

Molecular Weight

814.36

References & Citations

[1]Ushiki Y, et, al. Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4,5,6,7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors. Bioorg Med Chem Lett. 2022 Mar 1;59:128572.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-145894/NaPi2b-IN-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-145894/NaPi2b-IN-2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2227445-31-8

Available Sizes

Curated Selection

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