Macranthoin G

Macranthoin G is an inhibitor of p38 MAPK. Macranthoin G protects the cytotoxicity induced by Aβ or hydrogen peroxide in neuronal cells by downregulating p38 MAPK. Macranthoin G can used in study Alzheimer’s Disease[1].

Product Specifications

CAS Number

[159934-13-1]

Product Name Alternative

Methyl 3,5-dicaffeoyl quinic acid

UNSPSC

12352005

Target

P38 MAPK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/macranthoin-g.html

Solubility

10 mM in DMSO

Smiles

O=C(OC)[C@@](C1)(O)C[C@@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)[C@@H]1OC(/C=C/C3=CC(O)=C(O)C=C3)=O

Molecular Formula

C26H26O12

Molecular Weight

530.48

References & Citations

[1]Lee JK, et al. Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease. Molecules. 2017 Aug 2;22 (8) :1287.