Macranthoin G
Product Specifications
UNSPSC Description
Macranthoin G is an inhibitor of p38 MAPK. Macranthoin G protects the cytotoxicity induced by Aβ or hydrogen peroxide in neuronal cells by downregulating p38 MAPK. Macranthoin G can used in study Alzheimer’s Disease[1].
Target Antigen
p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/macranthoin-g.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)[C@@](C1)(O)C[C@@H](OC(/C=C/C2=CC(O)=C(O)C=C2)=O)[C@H](O)[C@@H]1OC(/C=C/C3=CC(O)=C(O)C=C3)=O
Molecular Weight
530.48
References & Citations
[1]Lee JK, et al. Recent Advances in the Inhibition of p38 MAPK as a Potential Strategy for the Treatment of Alzheimer's Disease. Molecules. 2017 Aug 2;22(8):1287.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N8453/Macranthoin-G-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N8453/
Clinical Information
No Development Reported
CAS Number
159934-13-1
Available Sizes
Curated Selection
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