2'-O-Methyladenosine

2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2].

Product Specifications

CAS Number

[2140-79-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/2-o-methyladenosine.html

Purity

99.94

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO

Molecular Formula

C11H15N5O4

Molecular Weight

281.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16 (5) :362-9.|[2]Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54 (2) :125-8.