M-AM-BBIQ

M-AM-BBIQ (compound 10) is a dual TLR7 and TLR8 agonist, with EC50 values of 0.12 μM and 1.7 μM for hTLR7 and hTLR8, respectively[1].

Product Specifications

CAS Number

[1258457-58-7]

UNSPSC

12352005

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/m-am-bbiq.html

Smiles

NC1=NC2=CC=CC=C2C3=C1N=C(CCCC)N3CC4=CC=CC(CN)=C4

Molecular Formula

C22H25N5

Molecular Weight

359.47

References & Citations

[1]Kushvinder Kumar, et al. Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption. ACS Med. Chem. Lett. 2024, July. 22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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