PROTAC PARP1 degrader-2

PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50IC50 [1]

Product Specifications

CAS Number

[2923686-62-6]

UNSPSC

12352005

Target

PARP; PROTACs

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-parp1-degrader-2.html

Smiles

O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC5CCN(CC5)C6=CC7=C(C(N(C8CCC(NC8=O)=O)C7=O)=O)C=C6

Molecular Formula

C38H37F2N9O6

Molecular Weight

753.75

References & Citations

[1]Li Y, et al., Parp-1 degradation agent and use thereof. WO2023066363.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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