PROTAC PARP1 degrader-2
PROTAC PARP1 degrader-2 (Compound 72) is a PROTAC degrader for PARP with a DC50IC50 [1]
Product Specifications
CAS Number
[2923686-62-6]
UNSPSC
12352005
Target
PARP; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-parp1-degrader-2.html
Smiles
O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC5CCN(CC5)C6=CC7=C(C(N(C8CCC(NC8=O)=O)C7=O)=O)C=C6
Molecular Formula
C38H37F2N9O6
Molecular Weight
753.75
References & Citations
[1]Li Y, et al., Parp-1 degradation agent and use thereof. WO2023066363.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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