Quinethazone

Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. Quinethazone can be used for hypertension research[1][2].

Product Specifications

CAS Number

[73-49-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/quinethazone.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC2=C(NC(CC)NC2=O)C=C1Cl)(N)=O

Molecular Formula

C10H12ClN3O3S

Molecular Weight

289.74

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]FREED SC. MECHANISM OF ANTI-HYPERTENSIVE ACTION OF QUINETHAZONE. Proc Soc Exp Biol Med. 1963 Nov;114:421-2.|[2]Angelopoulos B, et al. Experimental investigation and observations on the diuretic action of quinethazone. Med Pharmacol Exp Int J Exp Med. 1966;14 (6) :528-36.