Indan-5-sulphonamide

Indan-5-sulphonamide (Compd 1) is a carbonic anhydrase inhibitor and anticonvulsant agent, with Ki values of 0.039 nM (hCA XII), 6.5 nM (hCA XIV) and 5.1 nM (hCA XIV), respectively[1].

Product Specifications

CAS Number

[35203-93-1]

Product Name Alternative

NSC 91508

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/indan-5-sulphonamide.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC2=C(CCC2)C=C1)(N)=O

Molecular Formula

C9H11NO2S

Molecular Weight

197.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Anne Thiry, et al. Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. Eur J Med Chem. 2008 Dec;43 (12) :2853-60.