AV-105

AV-105 is a Florbetapir (18F) -radiolabeled slyrylpyridine tosylate precursor extracted from patent WO2010078370A1, example 1.5. AV-105 can synthesize 18F-radiolabeled compounds, which are used for positron emission tomography (PET) imaging of neurodegenerative diseases of the brain[1].

Product Specifications

CAS Number

[1205550-99-7]

UNSPSC

12352005

Hazard Statement

H319

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/av-105.html

Concentration

10mM

Purity

99.70

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)N(C)C1=CC=C(/C=C/C2=CC=C(OCCOCCOCCOS(=O)(C3=CC=C(C)C=C3)=O)N=C2)C=C1

Molecular Formula

C32H40N2O8S

Molecular Weight

612.73

Precautions

H319

References & Citations

[1]Tyler Benedum, et al. Synthesis of 18f-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof. WO2010078370A1.