Heptaminol (hydrochloride) (Standard)
Product Specifications
UNSPSC Description
Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels[1][2][3].
Target Antigen
Others
Type
Reference Standards
Related Pathways
Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/heptaminol-hydrochloride-standard.html
Smiles
CC(O)(C)CCCC(N)C.[H]Cl
Molecular Weight
181.70
References & Citations
[2]Reiter M. Die indirekt sympathicomimetische Wirkung von Heptaminol auf den Herzmuskel [Indirect sympathomimetic effect of heptaminol on heart muscle]. Naunyn Schmiedebergs Arch Pharmakol. 1970;267(2):114-22. German.|[3]Chung JF, et al. NO-dependent attenuation of TPA-induced immunoinflammatory skin changes in Balb/c mice by pindolol, heptaminol or ATRA, but not by verapamil. Oncotarget. 2016 Jul 26;7(30):47576-47585.|[1]Pourrias B, et al. Heptaminol chlorhydrate: new data. Ann Pharm Fr. 1991;49(3):127-138.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1231R/Heptaminol-hydrochloride-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1231R/
CAS Number
543-15-7
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