BAY 249716
BAY 249716 stabilizes all three p53 protein variants. BAY 249716 also has antitubercular activity (IC90: [1][2].
Product Specifications
CAS Number
[696628-24-7]
UNSPSC
12352005
Target
Bacterial; MDM-2/p53
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/bay-249716.html
Purity
99.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CN=C(NC2=NC(C3=CC=CC=N3)=CS2)C=C1
Molecular Formula
C13H9ClN4S
Molecular Weight
288.76
References & Citations
[1]Lemos C, et al. Identification of Small Molecules that Modulate Mutant p53 Condensation. iScience. 2020 Sep 1;23 (9) :101517. |[2]Ananthan S, et al. High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv. Tuberculosis (Edinb) . 2009 Sep;89 (5) :334-53.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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