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OT-551

Product Specifications

UNSPSC Description

OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research[1][2].

Target Antigen

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ot-551.html

Solubility

10 mM in DMSO

Smiles

CC1(C)CC(OC(C2CC2)=O)CC(C)(C)N1O.[H]Cl

Molecular Weight

277.79

References & Citations

[1]Masaki Tanito, et al. Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats. Exp Eye Res. 2010 Jul;91(1):111-4. |[2]S. A. Mousa, et al. Anti-Angiogenesis Efficacy of the Novel NF-B and Oxidative Stress Inhibitor, OT-551. ARVO Annual Meeting Abstract.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W556870/OT-551-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W556870/

Clinical Information

Phase 2

CAS Number

627085-15-8

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