Azulene
Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry[1][2][3].
Product Specifications
CAS Number
[275-51-4]
Product Name Alternative
Cyclopentacycloheptene
UNSPSC
12352005
Hazard Statement
H411
Target
HIV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/azulene.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C12=CC=CC=CC1=CC=C2
Molecular Formula
C10H8
Molecular Weight
128.17
Precautions
H411
References & Citations
[1]Teppo O Leino, et al. Azulene-based Compounds for Targeting Orexin Receptors. Eur J Med Chem. 2018 Sep 5;157:88-100.|[2]Julia Peet, et al. Antiretroviral (HIV-1) Activity of Azulene Derivatives. Bioorg Med Chem. 2016 Apr 15;24 (8) :1653-7.|[3]David A. Becker, et al. A new synthesis of substituted azulenes. Journal of the American Chemical Society, 111 (1), 389-391.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV
Available Sizes
Curated Selection
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