Imidazole-5-propionic acid

Imidazole-5-propionic acid (Imidazolepropionic acid) is a urinary metabolite of L-histidine (HY-N0832) . Imidazole-5-propionic acid can be used in the research of intestinal diseases and cardiovascular diseases[1][2][3].

Product Specifications

CAS Number

[1074-59-5]

Product Name Alternative

Imidazolepropionic acid

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Amino Acid Derivatives; Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cardiovascular Disease; Inflammation/Immunology; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/imidazole-5-propionic-acid.html

Purity

99.99

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

C(CC(=O)O)C1=CN=CN1

Molecular Formula

C6H8N2O2

Molecular Weight

140.14

Precautions

H315, H319, H335

References & Citations

[1]Wadud S, et al. In vitro catabolism of histidine by mixed rumen bacteria and protozoa. Curr Microbiol. 2001 Jan;42 (1) :12-7. |[2]van der Heiden C, et al. Increased urinary imidazolepropionic acid, N-acetylhistamine and other imidazole compounds in patients with intestinal disorders. Clin Chim Acta. 1972 Jun;39 (1) :201-14. |[3]Pinnelli VB, et al. The Role Played by Imidazole Propionic Acid in Modulating Gut-Heart Axis and the Development of Atherosclerosis: An Explorative Review. Cureus. 2025 Oct 11;17 (10) :e94362.