Trans-ACPD

Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons.

Product Specifications

CAS Number

[67684-64-4]

Product Name Alternative

Trans- (±) -ACP

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/trans-ACPD.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 3.57 mg/mL (ultrasonic)

Smiles

O=C([C@]1(N)C[C@@H](C(O)=O)CC1)O

Molecular Formula

C7H11NO4

Molecular Weight

173.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Linden DJ, et al. Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. J Neurophysiol. 1994 May;71 (5) :1992-8.|[2]Littman L, et al. Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis. J Neurochem. 1992 Nov;59 (5) :1893-904.|[3]Córdova MM, et al. Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice. Carbohydr Polym. 2013 Feb 15;92 (2) :2058-64.