Pantinin-1

Pantinin-1 is an antimicrobial peptide found in the venom of the Pandinus imperator scorpion. Pantinin-1 has potent antimicrobial activity against Gram-positive bacteria and fungi, weak antimicrobial activity against Gram-negative bacteria, and very low hemolytic activity against human erythrocytes. Pantinin-1 also has anticancer activity and can induce apoptosis in tumor cells[1].

Product Specifications

CAS Number

[2383114-96-1]

UNSPSC

12352209

Target

Apoptosis; Bacterial

Type

Peptides

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/pantinin-1.html

Smiles

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN

Molecular Formula

C75H119N17O18

Molecular Weight

1546.85

References & Citations

[1]Crusca Jr E, et al. Biophysical characterization and antitumor activity of synthetic Pantinin peptides from scorpion's venom[J]. Biochimica et Biophysica Acta (BBA) -Biomembranes, 2018, 1860 (11) : 2155-2165.