PIP5K1C-IN-1
Product Specifications
UNSPSC Description
PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pip5k1c-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC2=C(C31CCC3)C(C(N4)=CC5=C4C=C(Cl)C=C5)=NN2)NC6CC6
Molecular Weight
381.86
References & Citations
[1]Ochiai K, et al. Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163476/PIP5K1C-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163476/
Clinical Information
No Development Reported
Curated Selection
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