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CAPN6 Antibody [AMM02517G]

Product Specifications

Background

Tissue Location: Expressed only in placenta.

Synonyms

Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAPN6, CALPM, CANPX

Gene Name

CAPN6

Gene ID

827

UniProt

Q9Y6Q1

Chromosomal Location

Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle

Applications

WB

Dilution

WB--1:500~1:1000 WB--1:1000

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity) .

Molecular Weight

74576

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAPN6 Antibody [AMM02517G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=827

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6Q1

Available Sizes

Curated Selection

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