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CDKN2B Antibody (C-term) [APR04078G]

Product Specifications

Background

Tissue Location: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.

Synonyms

Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, MTS-2, p14-INK4b, p15-INK4b, p15INK4B, CDKN2B, MTS2

Gene Name

CDKN2B

Gene ID

1030

UniProt

P42772

Chromosomal Location

Cytoplasm. Note=Also found in the nucleus

Applications

WB, IF

Dilution

WB--1:1000 IF--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.

Molecular Weight

14722

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN2B Antibody (C-term) [APR04078G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1030

Uniprot URL

https://www.uniprot.org/uniprot/P42772

Available Sizes

Curated Selection

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