CDKN2B Antibody (C-term) [APR03720G]
Product Specifications
Background
Tissue Location: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
Synonyms
Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, MTS-2, p14-INK4b, p15-INK4b, p15INK4B, CDKN2B, MTS2
Gene Name
CDKN2B
Gene ID
1030
UniProt
P42772
Chromosomal Location
Cytoplasm. Note=Also found in the nucleus
Applications
WB, IHC-P, IF, FC
Dilution
WB--1:1000 IHC-P--1:100~500 IF--1:10~50 FC--1:10~50
Form
Function
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Molecular Weight
14722
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1030
Uniprot URL
https://www.uniprot.org/uniprot/P42772
Available Sizes
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