Procyanidin B-5 3,3'-di-O-gallate
Product Specifications
UNSPSC Description
Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/procyanidin-b-5-3-3-di-o-gallate.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@@H](C3=C(O)C=C(O[C@H](C4=CC(O)=C(C=C4)O)[C@@H](C5)OC(C6=CC(O)=C(C(O)=C6)O)=O)C5=C3O)C7=C(O)C=C(O)C=C7O[C@@H]2C8=CC(O)=C(C=C8)O
Molecular Weight
882.73
References & Citations
[1]Abe I, et al. Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis. Planta Med. 2000 Dec;66(8):753-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9777/Procyanidin-B-5-3-3-di-O-gallate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9777/
Clinical Information
No Development Reported
CAS Number
106533-60-2
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