SYNJ2 Antibody (Center) [AMM08068G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SYNJ2 Antibody (Center) [AMM08068G].

Synonyms

Synaptojanin-2, Synaptic inositol 1,5-trisphosphate 5-phosphatase 2, SYNJ2, KIAA0348

Gene Name

SYNJ2

Gene ID

8871

UniProt

O15056

Chromosomal Location

Cytoplasm. Cell membrane. Membrane raft. Cell junction, synapse, presynapse {ECO:0000250|UniProtKB:O55207}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O55207}. Note=Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (By similarity) Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11084340) .

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.