PGF Antibody (Center) [APR09073G]
Product Specifications
Background
Tissue Location: While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PGF Antibody (Center) [APR09073G].
Synonyms
Placenta growth factor, PlGF, PGF, PGFL, PLGF
Gene Name
PGF
Gene ID
5228
UniProt
P49763
Chromosomal Location
Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Molecular Weight
24789
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5228
Uniprot URL
https://www.uniprot.org/uniprot/P49763
Available Sizes
Curated Selection
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