UP158
Product Specifications
UNSPSC Description
UP158 enhances the activity of ATPase, and activates valosin-containing protein (VCP) with an EC50 of 2.57 μM[1].
Target Antigen
p97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/up158.html
Smiles
ClC1=CC2=C(NC3=C(N4CCC5(CC4)OCCO5)N=CN=C32)C=C1
Molecular Weight
344.80
References & Citations
[1]Phan JM, et al., VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models. J Clin Invest. 2024 May 23;134(14):e169039.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168324/UP158-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168324/
Clinical Information
No Development Reported
CAS Number
489402-33-7
Curated Selection
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