CES2-IN-1
CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor (IC50: 6.72 μM for human CES2) . CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan (HY-16562) -induced delayed diarrhea and DSS-induced ulcerative colitis[1].
Product Specifications
UNSPSC
12352005
Target
Carboxylesterase (CES)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hces2-in-1.html
Purity
98.18
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=CC=CC2=C1N=C(C=C2)NC3=NC4=CC=CC=C4N3
Molecular Formula
C16H11ClN4
Molecular Weight
294.74
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155181/hCES2-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155181/hCES2-IN-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CES2
CAS Number
[2994634-52-3]
Available Sizes
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