2,4-D

2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].

Product Specifications

CAS Number

[94-75-7]

Product Name Alternative

2,4-Dichlorophenoxyacetic acid

UNSPSC

12352005

Hazard Statement

H302, H317, H318, H335, H412

Target

Apoptosis; DNA/RNA Synthesis

Type

Natural Products

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-4-d.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

O=C(O)COC1=CC=C(Cl)C=C1Cl

Molecular Formula

C8H6Cl2O3

Molecular Weight

221.04

Precautions

H302, H317, H318, H335, H412

References & Citations

[1]Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57 (2) :302-10.|[2]Ganguli A, et al. 2, 4-Dichlorophenoxyacetic acid induced toxicity in lung cells by disruption of the tubulin-microtubule network. Toxicology Research, 2014, 3 (2) : 118-130.|[3]Marouani N, et al. Effects of oral administration of 2,4-dichlorophenoxyacetic acid (2,4-D) on reproductive parameters in male Wistar rats. Environ Sci Pollut Res Int. 2017 Jan;24 (1) :519-526.