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JR-6

Product Specifications

UNSPSC Description

JR-6 is a Gi/o pathway biased and muscarinic M2 selective partial agonist[1].

Target Antigen

mAChR

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jr-6.html

Solubility

10 mM in DMSO

Smiles

C[N+]1(CC2=CC=CS2)CC=CCC1.[Cl-]

Molecular Weight

229.77

References & Citations

[1]Nelic D, et al. Agonist-selective activation of individual G-proteins by muscarinic receptors. Sci Rep. 2024 Apr 26;14(1):9652.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-162491/JR-6-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-162491/

Clinical Information

No Development Reported

Curated Selection

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