JR-6
JR-6 is a Gi/o pathway biased and muscarinic M2 selective partial agonist[1].
Product Specifications
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jr-6.html
Solubility
10 mM in DMSO
Smiles
C[N+]1(CC2=CC=CS2)CC=CCC1.[Cl-]
Molecular Formula
C11H16ClNS
Molecular Weight
229.77
References & Citations
[1]Nelic D, et al. Agonist-selective activation of individual G-proteins by muscarinic receptors. Sci Rep. 2024 Apr 26;14 (1) :9652.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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