Bilobalide (Standard)
Product Specifications
UNSPSC Description
Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons[1][2].
Target Antigen
Apoptosis; Autophagy; Endogenous Metabolite
Type
Reference Standards
Related Pathways
Apoptosis;Autophagy;Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bilobalide-standard.html
Smiles
O=C(O1)C[C@@]2([C@]1([H])C[C@]3(C(C)(C)C)O)[C@@]34[C@](OC([C@@H]4O)=O)([H])OC2=O
Molecular Weight
326.30
References & Citations
[1]O Weichel, et al. Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus. Naunyn Schmiedebergs Arch Pharmacol. 1999 Dec;360(6):609-15.|[2]Chun Shi, et al. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Apoptosis. 2010 Jun;15(6):715-27.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0076R/Bilobalide-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0076R/
CAS Number
33570-04-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Cytokeratin 7 Antibody (rKRT7/8763) [Alexa Fluor 350]](https://cdn.genprice.uk/genprice/genprice3.png)
NBP3-20717AF350 0.1 mL
Mouse Monoclonal Cytokeratin 7 Antibody (rKRT7/8763) [Alexa Fluor 350]
Ask
View Details 