BDC2.5 mimotope 1040-31 (TFA)
BDC2.5 mimotope 1040-31 TFA, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells[1][2].
Product Specifications
UNSPSC
12352209
Target
Transmembrane Glycoprotein
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bdc2-5-mimotope-1040-31-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O.OC(C(F)(F)F)=O
Molecular Formula
C63H97N17O14S.xC2HF3O2
Molecular Weight
1348.61 (free acid)
References & Citations
[1]Dai YD, et al. A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas. J Immunol. 2005 Sep 15;175 (6) :3621-7.|[2]Masteller EL, et al. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J Immunol. 2005 Sep 1;175 (5) :3053-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1822A/BDC2-5-mimotope-1040-31-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1822A/
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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