BDC2.5 mimotope 1040-31 (TFA)

BDC2.5 mimotope 1040-31 TFA, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg+ T cells[1][2].

Product Specifications

UNSPSC

12352209

Target

Transmembrane Glycoprotein

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/bdc2-5-mimotope-1040-31-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O.OC(C(F)(F)F)=O

Molecular Formula

C63H97N17O14S.xC2HF3O2

Molecular Weight

1348.61 (free acid)

References & Citations

[1]Dai YD, et al. A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas. J Immunol. 2005 Sep 15;175 (6) :3621-7.|[2]Masteller EL, et al. Expansion of functional endogenous antigen-specific CD4+CD25+ regulatory T cells from nonobese diabetic mice. J Immunol. 2005 Sep 1;175 (5) :3053-9.