FLT3-IN-27
Product Specifications
UNSPSC Description
FLT3-IN-27 (compound 49) is a FLT3-ITD inhibitor with the IC50 of 174 nM. FLT3-IN-27 inhibits cell growth and increases the number of cells in the G1 phase of the cell cycle and can be used for study of acute myeloid leukemia[1].
Target Antigen
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-27.html
Smiles
O=C(NC1=NN=C(SC2=C3C(OC(C4=CC=CC=C4)=C3)=NC=N2)S1)NC5=CC=C(OC)C=C5
Molecular Weight
476.53
References & Citations
[1]Moradi M, et al. Identification of furo[2,3-d]pyrimidin-4-ylsulfanyl-1,3,4-thiadiazole derivatives as novel FLT3-ITD inhibitors. Eur J Med Chem. 2024 Oct 12;280:116962.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168213/FLT3-IN-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168213/
Clinical Information
No Development Reported
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