Anti-CD19 (clone huB4)-SPDB-DM4 ADC

This ADC product is comprised of an anti-CD19 monoclonal antibody (clone hBU12) conjugated via a SPDB linker to a DM4. The DM4 is targeted to ceRoom Temperatureain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, DM4 binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death.