ISQ-1 (hydrochloride)
ISQ-1 hydrochloride is an isoquinolinone (IKur) blocker with potential atrial arrhythmic activity. ISQ-1 exhibits cardiac electrophysiological characteristics similar to another structurally distinct IKur blocker previously reported from our laboratory[1].
Product Specifications
CAS Number
[405165-77-7]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isq-1-hydrochloride.html
Smiles
O=C1N(C(CN(C)C)=C(C2=C1C=CC(OC)=C2)C3=CC=CC=C3)C.[H]Cl
Molecular Formula
C20H23ClN2O2
Molecular Weight
358.86
References & Citations
[1]In vivo cardiac electrophysiologic and antiarrhythmic effects of an isoquinoline IKur blocker, ISQ-1, in rat, dog, and nonhuman primate
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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