ISQ-1 (hydrochloride)

ISQ-1 hydrochloride is an isoquinolinone (IKur) blocker with potential atrial arrhythmic activity. ISQ-1 exhibits cardiac electrophysiological characteristics similar to another structurally distinct IKur blocker previously reported from our laboratory[1].

Product Specifications

CAS Number

[405165-77-7]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/isq-1-hydrochloride.html

Smiles

O=C1N(C(CN(C)C)=C(C2=C1C=CC(OC)=C2)C3=CC=CC=C3)C.[H]Cl

Molecular Formula

C20H23ClN2O2

Molecular Weight

358.86

References & Citations

[1]In vivo cardiac electrophysiologic and antiarrhythmic effects of an isoquinoline IKur blocker, ISQ-1, in rat, dog, and nonhuman primate

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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