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JG-2016

JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1) with an IC50 of 14.8 μM. JG-2016 can inhibit the growth of multiple tumor cells and has anti-tumor activity[1].

Product Specifications

CAS Number

[2887480-87-5]

UNSPSC

12352005

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jg-2016.html

Purity

98.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1)N=C2N(CCOCC(C)C)C3=CC(CC)=C(Cl)C=C3N=C2C1=O

Molecular Formula

C18H21ClN4O3

Molecular Weight

376.84

References & Citations

[1]Joshua James GRUBER, et al. Modulators of histone acetyltransferase 1 and methods of treatment thereof. Patent, WO2022272313A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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