AZ12559322
AZ12559322 is a positive allosteric modulator of mGluR2, with the Ki value of 1.31 nM. AZ12559322 can be used in neurological research[1].
Product Specifications
CAS Number
[947184-66-9]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/az12559322.html
Smiles
CC(C=C1C2=CC(NS(C)(=O)=O)=CC=C2)=C3C(N(CC3=C1)C(C)C)=O
Molecular Formula
C19H22N2O3S
Molecular Weight
358.45
References & Citations
[1]Li, Yinlong, et al. "Radiosynthesis and Evaluation of 11C-Labeled Isoindolone-Based Positive Allosteric Modulators for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor 2." ACS Pharmacology & Translational Science (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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