P11

P11 is a selective inhibitor of platelet-activating factor acetylhydrolases (PAFAHs) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC50 values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively[1].

Product Specifications

CAS Number

[942285-55-4]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p11.html

Purity

99.69

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=S(N1[C@](C2=CC=C(C=C2)C(C)(C)C)([H])C(C(O)=O)=CC[C@@]1([H])C3=CC=C(C=C3)C)(C4=CC=C(C=C4)C)=O

Molecular Formula

C30H33NO4S

Molecular Weight

503.65

References & Citations

[1]Jae Won Chang, et al. Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. ACS Chem Biol. 2015 Apr 17;10 (4) :925-32.