RO495
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase) [1].
Product Specifications
CAS Number
[1258296-60-4]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ro495.html
Purity
98.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(NC2=NC(N)=NC(C)=C2)=NC=C1)C3=C(Cl)C=CC=C3Cl
Molecular Formula
C17H14Cl2N6O
Molecular Weight
389.24
References & Citations
[1]Tobie D. Lee, et al. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology November 2019, 96 (5) 629-640.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15327155 1 Vial
Lentiviral human MCIDAS shRNA (UAS) - Lentiviral human MCIDAS shRNA (UAS, GFP) (25)
Ask
View Details 
