Brevicidine
Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negative pathogens. Brevicidine disrupts the morphology of bacteria by binding to polysaccharides (LPS) on bacterial cell membranes to form holes[1].
Product Specifications
CAS Number
[2676889-05-5]
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/brevicidine.html
Smiles
O=C(N[C@@](C(NCC(N[C@H](C(O[C@@H]1C)=O)CO)=O)=O)([H])[C@@H](C)CC)[C@H]1NC([C@@H](NC([C@@H](CCCN)NC(CNC([C@H](CCCN)NC([C@@H](CCCN)NC([C@H](NC([C@H](NC([C@@H](CC(N)=O)NC(CCC(C)CC)=O)=O)CC2=CC=C(C=C2)O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O
Molecular Formula
C74H106N18O17
Molecular Weight
1519.74
References & Citations
[1]Zhao X, et al. Mimicry of a non-ribosomally produced antimicrobial, brevicidine, by ribosomal synthesis and post-translational modification[J]. Cell Chemical Biology, 2020, 27 (10) : 1262-1271. e4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10519/Brevicidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10519/
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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