TR antagonist 1
Product Specifications
UNSPSC Description
TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively.
Target Antigen
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/_E_-3--3,5-Dibromo-4--4-hydroxy-3-isopropyl-5-_2-_pyridin-4-yl_ethenyl_phenoxy-phenyl-propionic_acid.html
Purity
99.57
Solubility
DMSO : ≥ 83.3 mg/mL
Smiles
O=C(O)CCC1=CC(Br)=C(OC2=CC(/C=C/C3=CC=NC=C3)=C(O)C(C(C)C)=C2)C(Br)=C1
Molecular Weight
561.26
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111443/TR-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111443/TR-antagonist-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
500794-88-7
Available Sizes
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