Estradiol

Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2].

Product Specifications

CAS Number

[50-28-2]

Product Name Alternative

β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol

UNSPSC

12352005

Hazard Statement

H351, H360, H362, H410

Target

Bacterial; Endogenous Metabolite; Estrogen Receptor/ERR

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Estradiol.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 16.67 mg/mL (ultrasonic)

Smiles

C[C@@]1([C@H]2O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O)=C3)([H])[C@]4([H])CC1

Molecular Formula

C18H24O2

Molecular Weight

272.39

Precautions

H351, H360, H362, H410

References & Citations

[1]Elham Hasanzadeh. Defining the role of 17β-estradiol in human endometrial stem cells differentiation into neuron-like cells. Cell Biol Int. 2021 Jan;45 (1) :140-153. |[2]Yujiao Lu, et al. Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory. J Neurosci. 2019 Apr 10;39 (15) :2792-2809.