SRC antibody
Product Specifications
Background
SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.
Synonyms
Proto-oncogene tyrosine-protein kinase Src|Proto-oncogene c-Src|pp60c-src (p60-Src) |SRC|SRC1
Gene ID
6714
UniProt
P12931
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Target
SRC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa, 60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1-79aa
Curated Selection
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