RECK antibody
Product Specifications
Background
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Synonyms
Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) |Suppressor of tumorigenicity 15 protein|RECK|ST15
Gene ID
8434
UniProt
O95980
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Reversion-inducing-cysteine-rich protein with kazal motifs
Target
RECK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cell Division and Proliferation, cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
110-210AA
Curated Selection
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