PRMT5 antibody
Product Specifications
Background
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
Protein arginine N-methyltransferase 5 (PRMT5) |72 kDa ICln-binding protein|Histone-arginine N-methyltransferase PRMT5|Jak-binding protein 1|Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs) |Protein arginine N-methyltransferase 5, N-terminally processed|PRMT5|HRMT1L5|IBP72|JBP1|SKB1
Gene ID
10419
UniProt
O14744
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Protein arginine methyltransferase 5
Target
PRMT5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
76-291aa
Curated Selection
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