MIF antibody
Product Specifications
Background
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Synonyms
Macrophage migration inhibitory factor (MIF) |Glycosylation-inhibiting factor (GIF) |L-dopachrome isomerase|L-dopachrome tautomerase|Phenylpyruvate tautomerase|MIF|GLIF|MMIF
Gene ID
4282
UniProt
P14174
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Target
MIF
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IP, IF
Field of Research
Immunology, Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IP, IF
Curated Selection
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