LC3 antibody
Product Specifications
Background
Map1LC3, also known as LC3, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. Three human Map1LC isoforms, MAP1LC3A, MAP1LC3B, and MAP1LC3C, undergo post-translational modifications during autophagy. And they differ in their post-translation modifications during autophagy. Map1LC3 also exists in two modified forms, an 18-kDa cytoplasmic form that was originally identified as a subunit of the microtubule-associated protein 1, and a 16-kDa form that is associated with the autophagosome membrane. This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C.
Synonyms
Microtubule-associated proteins 1A/1B light chain 3B|Autophagy-related protein LC3 B|Autophagy-related ubiquitin-like modifier LC3 B|MAP1 light chain 3-like protein 2|MAP1A/MAP1B light chain 3 B (MAP1A/MAP1B LC3 B) |Microtubule-associated protein 1 light chain 3 beta|MAP1LC3B|MAP1ALC3
Gene ID
81631
UniProt
Q9GZQ8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Microtubule-associated protein 1 light chain 3 beta
Target
LC3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Neuroscience, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
16 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
Immunogen Sequence
1-125aa
Curated Selection
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