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LAS1L antibody

Product Specifications

Background

Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Synonyms

Ribosomal biogenesis protein LAS1L|Endoribonuclease LAS1L|Protein LAS1 homolog|LAS1L

Gene ID

81887

UniProt

Q9Y4W2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

LAS1-like

Target

LAS1L

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

83 kDa, 70-75 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

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