NOS2 antibody
Product Specifications
Background
NOS2, also named as iNOS and NOS2A, produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NOS2 is a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. This antibody is specific to NOS2.
Synonyms
Nitric oxide synthase, inducible|Hepatocyte NOS (HEP-NOS) |Inducible NO synthase (Inducible NOS, iNOS) |NOS type II|Peptidyl-cysteine S-nitrosylase NOS2|NOS2|NOS2A
Gene ID
4843
UniProt
P35228
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Nitric oxide synthase 2, inducible
Target
NOS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
131 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
Immunogen Sequence
19-221aa
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